The Involvement of Heparan Sulfate (HS) in FGF1/HS/FGFR1 Signaling Complex
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چکیده
منابع مشابه
The involvement of heparan sulfate (HS) in FGF1/HS/FGFR1 signaling complex.
Fibroblast growth factor (FGF) signaling begins with the formation of a ternary complex of FGF, FGF receptor (FGFR), and heparan sulfate (HS). Multiple models have been proposed for the ternary complex. However, major discrepancies exist among those models, and none of these models have evaluated the functional importance of the interacting regions on the HS chains. To resolve the discrepancies...
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ژورنال
عنوان ژورنال: Journal of Biological Chemistry
سال: 2003
ISSN: 0021-9258
DOI: 10.1074/jbc.m212590200